A Pheromone is a chemical produced by a given species that affects the behavior or physiology of the same species. John J. McGlone, PhD "The Pheromone Site" Texas Tech University, Labratory of Animal Behavior, Physiology, and Behavior, www.depts.ttu.edu/animalwelfare/research/pheromones/

Mammals sense chemical signals in aerosol or for liquid from. There are many olfactory organs. The two most prominent olfactory organs are the main olfactory epithelium with it is associated olfactory bulb and the vomeronasal organ which transmits neurons to the accessory and main olfactory bulbs. As a general, historical convention, aerosol chemicals were perceived by the Main Olfactory Epithelium (MOE) and liquid signals by the Vomeronasal Organ (VNO). And pheromones were thought to be sensed by the VNO. We know now that mammalian pheromones can be sensed by either the MOE or the VNO. However, the MOE perceives primarily gas or aerosolized chemicals and the VNO primarily liquid signals. John J. McGlone, PhD "The Pheromone Site - How do Pheromones Work?" Texas Tech University, Labratory of Animal Behavior, Physiology, and Behavior, www.depts.ttu.edu/animalwelfare/research/pheromones/

Pheromone: Pheromones are chemicals produced by one species that affect the physiology or behavior of animals of the same species. vs. Interomone: An Interomone is a chemical produced and released by one species that has an effect on another species' behavior or physiology. John J. McGlone, Ph.D. "The Pheromone and Interomone Concepts" Texas Tech University, Laboratory of Animal Behavior, Physiology, and Behavior, www.depts.ttu.edu/animalwelfare/research/pheromones/

We license our proprietary pheromone technology to select partners around the world. Please contact us here if you want to discuss this opportunity.

UnRuffled Pets® is a superior, patented pheromone technology designed to support calm behavior in cats and dogs. Backed by decades of scientific research, our innovation is built on a deep understanding of how pheromones influence animal behavior. UnRuffled Pets® pheromone technology works by mimicking the natural chemical signals that animals use to communicate safety and reassurance. In the wild, mother cats and dogs release comforting pheromones to help their young feel secure. These same types of signals—when precisely replicated—can have a calming effect on adult animals as well. Our scientists have identified and synthesized species-specific pheromones that tap into this natural communication system. When released into a pet’s environment (through diffusers, sprays, or wearable products), the pheromones bind to receptors in the animal’s brain associated with emotional regulation. This interaction triggers a sense of calm, helping to reduce stress-related behaviors such as hiding, barking, scratching, pacing, or spraying. UnRuffled Pet's patented formulation is the result of extensive research into pheromone structures, behavior patterns, and molecular biology. The result: a clinically proven technology that delivers reliable, measurable calming effects—without sedation or pharmaceuticals.